Question 1

In normal people, IgA exists as both a dimer and a monomer.

Accepted Answer

A) True 
 B)False

Question 2

State the important stages of B cell development from stem cell to plasma cell and the main event happening at each stage.

Accepted Answer

1. Hematopoietic stem cell-stimulated to...

Question 3

All of the following is TRUE about IgM except

Accepted Answer

A)  most efficient activator of complement via the classic pathway.
B)  first antibody class to be secreted in a primary infection.
C)  contains a J chain.
D)  contains a secretory piece.
E)  is a pentamer.F) All of the above
G) A) and B)

Question 4

Which of the following are components of an antibody? (Check all that apply.)

Accepted Answer

A)  Two identical light chains
B)  Disulfide bonds
C)  Two identical heavy chains
D)  Carbohydrate
E)  All of the aboveF) C) and D)
G) A) and D)

Question 5

What kind of antigens can B lymphocytes react against independent of T helper cells?

Accepted Answer

A)  Large molecules with repetitive structures.
B)  Small molecules that can react directly with the B cell receptor.
C)  Small molecules with repetitive structures.
D)  Large molecules that can react directly with the B cell receptor.E) All of the above
F) A) and B)

Question 6

Breast- fed infants are less vulnerable to infections than bottle- fed infants because of the IgG that passes into breast milk.

Accepted Answer

A) True 
 B)False

Question 7

In general, reagents containing polyclonal antibodies have fewer false positives than monoclonal antibodies but they are less sensitive.

Accepted Answer

A) True 
 B)False

Question 8

When a B cell encounters its corresponding antigen, it expresses more ________  in order to be a more effective antigen presenting cell.

Accepted Answer

A)  MHC Class I
B)  MHC Class II
C)  IL- 7 receptor
D)  IgM
E)  IgDF) A) and C)
G) A) and E)

Question 9

The portion of an antibody molecule that contains the antibody binding site is the

Accepted Answer

A)  heavy chain.
B)  Fc fragment.
C)  Fab fragment.
D)  light chain.E) B) and C)
F) A) and D)

Question 10

Each of the following statements regarding B lymphocytes is TRUE except

Accepted Answer

A)  B cells mature in the bone marrow and then leave to populate germinal centers in the secondary lymphoid tissue (spleen, lymph nodes, etc.) .
B)  Rearrangements of VDJ heavy chain genes and VJ light chain genes appear to be completely random.
C)  A B cell is considered to be fully matured when it is secreting antibody.
D)  When B cells encounter their corresponding antigen, they undergo rapid proliferation and conversion to plasma cells.E) B) and C)
F) A) and D)

Question 11

Which of the following is(are) characteristic of a plasma cell?

Accepted Answer

A)  It secretes identical antibodies all directed at a single unique epitope.
B)  It is the most rapidly dividing B cell.
C)  It no longer expresses membrane IgD, only IgM.
D)  All of the above.E) A) and B)
F) A) and C)

Question 12

When a B cell reacts directly against an antigen, independent of T helper cells, does it produce antibody?

Accepted Answer

A)  Yes, usually IgE.
B)  No.
C)  Yes, usually IgG.
D)  Yes, usually IgA.
E)  Yes, usually IgM.F) A) and B)
G) A) and C)

Question 13

When immunoglobulin genes are rearranged to make a mature B cell, large sections of DNA are deleted, and the gene rearrangement is irreversible.

Accepted Answer

A) True 
 B)False

Question 14

The most abundant immunoglobulin in human serum is ________ while the most abundant immunoglobulin in human secretions is ________ .

Accepted Answer

The answer of The most abundant immunoglobulin in human serum...

Question 15

Antibody heavy and light chains have one end called the ________ region, which is coded for by the VDJ and VJ DNA rearrangements and which binds to antigen.

Accepted Answer

variable o...

Question 16

The type of antibody produced by a hybridoma cell is called ________.

Accepted Answer

The answer of The type of antibody produced by a...

Question 17

The Fc portion of the antibody molecule contains important binding sites for

Accepted Answer

A)  complement.
B)  antigen.
C)  interleukins.
D)  interferons.E) B) and D)
F) All of the above

Question 18

Mature, unstimulated B cells leave the bone marrow and take up residence in the spleen, tonsils, mucosal- associated lymphoid tissue, and lymph nodes.

Accepted Answer

A) True 
 B)False

Question 19

The class of antibodies responsible for one form of allergies is IgE.

Accepted Answer

A) True 
 B)False

Question 20

An IgG molecule is composed of two gamma heavy chains, one lambda light chain and one kappa light chain.

Accepted Answer

A) True 
 B)False

Exam 3: Immunoglobulins

When immunoglobulin genes are rearranged to make a mature B cell, large sections of DNA are deleted, and the gene rearrangement is irreversible.

Correct AnswerverifiedShow Answer

When a B cell reacts directly against an antigen, independent of T helper cells, does it produce antibody?

Correct AnswerverifiedShow Answer

In normal people, IgA exists as both a dimer and a monomer.

Correct AnswerverifiedShow Answer

In general, reagents containing polyclonal antibodies have fewer false positives than monoclonal antibodies but they are less sensitive.

Correct AnswerverifiedShow Answer

Mature, unstimulated B cells leave the bone marrow and take up residence in the spleen, tonsils, mucosal- associated lymphoid tissue, and lymph nodes.

Correct AnswerverifiedShow Answer

The type of antibody produced by a hybridoma cell is called ________.

Correct AnswerverifiedShow Answer

The most abundant immunoglobulin in human serum is ________ while the most abundant immunoglobulin in human secretions is ________ .

Correct AnswerverifiedShow Answer

All of the following is TRUE about IgM except

Correct AnswerverifiedShow Answer

Each of the following statements regarding B lymphocytes is TRUE except

Correct AnswerverifiedShow Answer

The portion of an antibody molecule that contains the antibody binding site is the

Correct AnswerverifiedShow Answer

Which of the following is(are) characteristic of a plasma cell?

Correct AnswerverifiedShow Answer

State the important stages of B cell development from stem cell to plasma cell and the main event happening at each stage.

Correct Answerverified1. Hematopoietic stem cell-stimulated to...View AnswerShow Answer

What kind of antigens can B lymphocytes react against independent of T helper cells?

Correct AnswerverifiedShow Answer

When a B cell encounters its corresponding antigen, it expresses more ________ in order to be a more effective antigen presenting cell.

Correct AnswerverifiedShow Answer

An IgG molecule is composed of two gamma heavy chains, one lambda light chain and one kappa light chain.

Correct AnswerverifiedShow Answer

The class of antibodies responsible for one form of allergies is IgE.

Correct AnswerverifiedShow Answer

Antibody heavy and light chains have one end called the ________ region, which is coded for by the VDJ and VJ DNA rearrangements and which binds to antigen.

Correct Answerverifiedvariable o...View AnswerShow Answer

Which of the following are components of an antibody? (Check all that apply.)

Correct AnswerverifiedShow Answer

Breast- fed infants are less vulnerable to infections than bottle- fed infants because of the IgG that passes into breast milk.

Correct AnswerverifiedShow Answer

The Fc portion of the antibody molecule contains important binding sites for

Correct AnswerverifiedShow Answer

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The most abundant immunoglobulin in human serum is while the most abundant immunoglobulin in human secretions is .

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1. Hematopoietic stem cell-stimulated to...
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variable o...
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